Whispers of a disembodied spark howling alone in the desert are floating around Cybertron. Whispers of Starscream's loyalty to Megatron's cause are also floating around. Frustrated and needing some space to clear his head, Starscream visits the desert and is surprised to actually hear the rumored screams. He follows the sound and is met with a creature that makes him question what it means to be a cybernetic being.
Starscream faces off with this grotesque experiment in "I Have No Mouth And I Must Starscream," by Dan Watters (Home Sick Pilots, Lucifer, The Sandman Universe).