Written by
Brian Michael Bendis
Art by
John Totleben
 
Despondent that the funding for his cherished limb regeneration research is to be — pardon the pun — cut off, biologist Curt Conners turns himself into a guinea pig — and finds himself transformed into the lethal Lizard! The rapacious reptile seeks refuge in the dank recesses of the New York City sewer system — pursued by our fledgling web-spinner! But unknown to them both, something far more mysterious lurks in the subterranean shadows — something known as the macabre Man-Thing!
 
Featuring
First Appearances of Man-Thing (Theodore Sallis), Lizard (Curt Conners) from Earth-1610.